| El Puerto de Santa Maria to Selargius | 856.75 mi (1,378.81 km) |
| El Puerto de Santa Maria to Selvazzano Dentro | 1,113.88 mi (1,792.62 km) |
| El Puerto de Santa Maria to Senago | 1,009.06 mi (1,623.93 km) |
| El Puerto de Santa Maria to Senigallia | 1,134.18 mi (1,825.29 km) |
| El Puerto de Santa Maria to Seravezza | 1,003.67 mi (1,615.25 km) |
| El Puerto de Santa Maria to Seregno | 1,014.26 mi (1,632.29 km) |
| El Puerto de Santa Maria to Seriate | 1,036.70 mi (1,668.42 km) |
| El Puerto de Santa Maria to Sermoneta | 1,082.43 mi (1,742.00 km) |
| El Puerto de Santa Maria to Serramanna | 845.75 mi (1,361.10 km) |
| El Puerto de Santa Maria to Serravalle Pistoiese | 1,028.04 mi (1,654.47 km) |
| El Puerto de Santa Maria to Sessa Aurunca | 1,126.59 mi (1,813.07 km) |
| El Puerto de Santa Maria to Sesto Calende | 994.59 mi (1,600.63 km) |
| El Puerto de Santa Maria to Sesto Fiorentino | 1,043.03 mi (1,678.60 km) |
| El Puerto de Santa Maria to Sesto San Giovanni | 1,011.30 mi (1,627.52 km) |
| El Puerto de Santa Maria to Sestri Levante | 974.68 mi (1,568.59 km) |
