| Ellesmere Port to Sestu | 1,119.37 mi (1,801.45 km) |
| Ellesmere Port to Settimo Torinese | 739.01 mi (1,189.32 km) |
| Ellesmere Port to Seveso | 753.38 mi (1,212.45 km) |
| Ellesmere Port to Sezze | 1,099.57 mi (1,769.59 km) |
| Ellesmere Port to Siano | 1,189.20 mi (1,913.83 km) |
| Ellesmere Port to Siena | 946.03 mi (1,522.49 km) |
| Ellesmere Port to Signa | 913.73 mi (1,470.51 km) |
| Ellesmere Port to Silea | 859.00 mi (1,382.42 km) |
| Ellesmere Port to Silvi Paese | 1,076.70 mi (1,732.78 km) |
| Ellesmere Port to Sinalunga | 964.13 mi (1,551.61 km) |
| Ellesmere Port to Siniscola | 1,056.63 mi (1,700.48 km) |
| Ellesmere Port to Sinnai | 1,121.83 mi (1,805.41 km) |
| Ellesmere Port to Siracusa | 1,419.28 mi (2,284.10 km) |
| Ellesmere Port to Solaro | 753.16 mi (1,212.09 km) |
| Ellesmere Port to Soliera | 857.86 mi (1,380.60 km) |
