| Enniskillen to Sacile | 1,057.14 mi (1,701.30 km) |
| Enniskillen to Sala Consilina | 1,440.62 mi (2,318.45 km) |
| Enniskillen to Salemi | 1,493.33 mi (2,403.29 km) |
| Enniskillen to Salerno | 1,397.36 mi (2,248.83 km) |
| Enniskillen to Salo | 1,003.65 mi (1,615.22 km) |
| Enniskillen to Salsomaggiore Terme | 1,022.90 mi (1,646.20 km) |
| Enniskillen to Saluzzo | 950.23 mi (1,529.25 km) |
| Enniskillen to Salzano | 1,063.00 mi (1,710.73 km) |
| Enniskillen to Samarate | 942.60 mi (1,516.96 km) |
| Enniskillen to San Benedetto del Tronto | 1,250.27 mi (2,012.11 km) |
| Enniskillen to San Biagio di Callalta | 1,065.50 mi (1,714.76 km) |
| Enniskillen to San Bonifacio | 1,039.53 mi (1,672.97 km) |
| Enniskillen to San Casciano in Val di Pesa | 1,122.14 mi (1,805.91 km) |
| Enniskillen to San Cataldo | 1,548.57 mi (2,492.19 km) |
| Enniskillen to San Cesareo | 1,271.76 mi (2,046.70 km) |
