| Enniskillen to Spello | 1,206.57 mi (1,941.79 km) |
| Enniskillen to Spilamberto | 1,072.26 mi (1,725.63 km) |
| Enniskillen to Spilimbergo | 1,064.08 mi (1,712.47 km) |
| Enniskillen to Spinea | 1,066.43 mi (1,716.26 km) |
| Enniskillen to Spoleto | 1,218.93 mi (1,961.67 km) |
| Enniskillen to Spoltore | 1,284.14 mi (2,066.62 km) |
| Enniskillen to Spresiano | 1,056.33 mi (1,700.00 km) |
| Enniskillen to Squinzano | 1,523.94 mi (2,452.55 km) |
| Enniskillen to Statte | 1,487.17 mi (2,393.38 km) |
| Enniskillen to Stezzano | 970.60 mi (1,562.03 km) |
| Enniskillen to Strada | 1,130.30 mi (1,819.05 km) |
| Enniskillen to Stradella | 986.55 mi (1,587.69 km) |
| Enniskillen to Striano | 1,383.66 mi (2,226.79 km) |
| Enniskillen to Subiaco | 1,275.63 mi (2,052.93 km) |
| Enniskillen to Sulmona | 1,297.62 mi (2,088.31 km) |
