| Ermoupoli to Somma Lombardo | 1,010.80 mi (1,626.73 km) |
| Ermoupoli to Somma Vesuviana | 609.19 mi (980.40 km) |
| Ermoupoli to Sommacampagna | 911.15 mi (1,466.36 km) |
| Ermoupoli to Sona | 913.06 mi (1,469.43 km) |
| Ermoupoli to Sondrio | 979.54 mi (1,576.41 km) |
| Ermoupoli to Sora | 669.89 mi (1,078.09 km) |
| Ermoupoli to Sorbolo | 908.40 mi (1,461.94 km) |
| Ermoupoli to Soresina | 948.50 mi (1,526.46 km) |
| Ermoupoli to Sorisole | 972.56 mi (1,565.19 km) |
| Ermoupoli to Sorrento | 606.90 mi (976.71 km) |
| Ermoupoli to Sorso | 904.74 mi (1,456.04 km) |
| Ermoupoli to Sortino | 543.27 mi (874.31 km) |
| Ermoupoli to Soverato Marina | 463.12 mi (745.32 km) |
| Ermoupoli to Sovicille | 824.58 mi (1,327.03 km) |
| Ermoupoli to Spello | 750.38 mi (1,207.62 km) |
