| Esch-sur-Alzette to Senftenberg | 379.45 mi (610.66 km) |
| Esch-sur-Alzette to Siegburg | 105.16 mi (169.24 km) |
| Esch-sur-Alzette to Siegen | 131.48 mi (211.59 km) |
| Esch-sur-Alzette to Sigmaringen | 176.58 mi (284.17 km) |
| Esch-sur-Alzette to Simbach am Inn | 330.66 mi (532.15 km) |
| Esch-sur-Alzette to Simmerath | 77.52 mi (124.76 km) |
| Esch-sur-Alzette to Sindelfingen | 147.02 mi (236.61 km) |
| Esch-sur-Alzette to Sinsheim | 131.69 mi (211.93 km) |
| Esch-sur-Alzette to Sinzheim | 111.12 mi (178.83 km) |
| Esch-sur-Alzette to Sinzig | 91.82 mi (147.78 km) |
| Esch-sur-Alzette to Soest | 171.09 mi (275.34 km) |
| Esch-sur-Alzette to Solingen | 125.20 mi (201.49 km) |
| Esch-sur-Alzette to Soltau | 292.82 mi (471.25 km) |
| Esch-sur-Alzette to Sommerda | 254.00 mi (408.77 km) |
| Esch-sur-Alzette to Sondershausen | 250.79 mi (403.61 km) |
