| Esch-sur-Alzette to Orbetello | 548.22 mi (882.28 km) |
| Esch-sur-Alzette to Oria | 841.02 mi (1,353.50 km) |
| Esch-sur-Alzette to Oristano | 674.86 mi (1,086.08 km) |
| Esch-sur-Alzette to Orta Nova | 734.36 mi (1,181.84 km) |
| Esch-sur-Alzette to Orte | 574.82 mi (925.08 km) |
| Esch-sur-Alzette to Ortona | 637.61 mi (1,026.13 km) |
| Esch-sur-Alzette to Orvieto | 552.36 mi (888.94 km) |
| Esch-sur-Alzette to Orzinuovi | 337.88 mi (543.77 km) |
| Esch-sur-Alzette to Osimo | 547.19 mi (880.61 km) |
| Esch-sur-Alzette to Ospitaletto | 332.50 mi (535.10 km) |
| Esch-sur-Alzette to Ostuni | 826.81 mi (1,330.63 km) |
| Esch-sur-Alzette to Ottaviano | 725.78 mi (1,168.03 km) |
| Esch-sur-Alzette to Ovada | 358.25 mi (576.55 km) |
| Esch-sur-Alzette to Ozieri | 633.06 mi (1,018.80 km) |
| Esch-sur-Alzette to Paceco | 859.63 mi (1,383.44 km) |
