| Esch-sur-Alzette to Selargius | 724.77 mi (1,166.41 km) |
| Esch-sur-Alzette to Selvazzano Dentro | 392.60 mi (631.84 km) |
| Esch-sur-Alzette to Senago | 307.73 mi (495.25 km) |
| Esch-sur-Alzette to Senigallia | 526.51 mi (847.34 km) |
| Esch-sur-Alzette to Seravezza | 429.69 mi (691.53 km) |
| Esch-sur-Alzette to Seregno | 305.16 mi (491.11 km) |
| Esch-sur-Alzette to Seriate | 315.67 mi (508.02 km) |
| Esch-sur-Alzette to Sermoneta | 644.64 mi (1,037.46 km) |
| Esch-sur-Alzette to Serramanna | 710.85 mi (1,144.01 km) |
| Esch-sur-Alzette to Serravalle Pistoiese | 449.69 mi (723.71 km) |
| Esch-sur-Alzette to Sessa Aurunca | 688.37 mi (1,107.83 km) |
| Esch-sur-Alzette to Sesto Calende | 287.85 mi (463.25 km) |
| Esch-sur-Alzette to Sesto Fiorentino | 462.75 mi (744.72 km) |
| Esch-sur-Alzette to Sesto San Giovanni | 313.04 mi (503.79 km) |
| Esch-sur-Alzette to Sestri Levante | 395.15 mi (635.94 km) |
