| Esch-sur-Alzette to Setubal | 1,055.07 mi (1,697.98 km) |
| Esch-sur-Alzette to Sever do Vouga | 922.43 mi (1,484.51 km) |
| Esch-sur-Alzette to Silves | 1,113.41 mi (1,791.86 km) |
| Esch-sur-Alzette to Sines | 1,084.87 mi (1,745.94 km) |
| Esch-sur-Alzette to Sintra | 1,057.70 mi (1,702.21 km) |
| Esch-sur-Alzette to Sobrado de Paiva | 903.99 mi (1,454.84 km) |
| Esch-sur-Alzette to Sobral de Monte Agraco | 1,037.96 mi (1,670.43 km) |
| Esch-sur-Alzette to Soure | 966.36 mi (1,555.20 km) |
| Esch-sur-Alzette to Tabua | 929.00 mi (1,495.08 km) |
| Esch-sur-Alzette to Tavira | 1,092.52 mi (1,758.24 km) |
| Esch-sur-Alzette to Tomar | 981.82 mi (1,580.09 km) |
| Esch-sur-Alzette to Tondela | 923.00 mi (1,485.43 km) |
| Esch-sur-Alzette to Torre de Moncorvo | 854.60 mi (1,375.35 km) |
| Esch-sur-Alzette to Torres Novas | 992.85 mi (1,597.83 km) |
| Esch-sur-Alzette to Torres Vedras | 1,038.59 mi (1,671.45 km) |
