| Esch-sur-Alzette to Ruzomberok | 600.55 mi (966.49 km) |
| Esch-sur-Alzette to Sabinov | 679.94 mi (1,094.26 km) |
| Esch-sur-Alzette to Sal'a | 548.52 mi (882.76 km) |
| Esch-sur-Alzette to Samorin | 525.45 mi (845.63 km) |
| Esch-sur-Alzette to Senec | 526.02 mi (846.54 km) |
| Esch-sur-Alzette to Senica | 517.78 mi (833.28 km) |
| Esch-sur-Alzette to Sered' | 539.72 mi (868.59 km) |
| Esch-sur-Alzette to Skalica | 509.57 mi (820.07 km) |
| Esch-sur-Alzette to Smizany | 656.52 mi (1,056.56 km) |
| Esch-sur-Alzette to Snina | 729.12 mi (1,173.40 km) |
| Esch-sur-Alzette to Spisska Nova Ves | 658.36 mi (1,059.52 km) |
| Esch-sur-Alzette to Stara L'ubovna | 659.93 mi (1,062.06 km) |
| Esch-sur-Alzette to Stara Tura | 531.38 mi (855.18 km) |
| Esch-sur-Alzette to Stropkov | 704.34 mi (1,133.53 km) |
| Esch-sur-Alzette to Stupava | 508.66 mi (818.60 km) |
