| Estepa to Spello | 1,004.67 mi (1,616.86 km) |
| Estepa to Spilamberto | 966.62 mi (1,555.62 km) |
| Estepa to Spilimbergo | 1,097.13 mi (1,765.65 km) |
| Estepa to Spinea | 1,046.06 mi (1,683.48 km) |
| Estepa to Spoleto | 1,000.70 mi (1,610.47 km) |
| Estepa to Spoltore | 1,066.95 mi (1,717.10 km) |
| Estepa to Spresiano | 1,059.07 mi (1,704.40 km) |
| Estepa to Squinzano | 1,248.87 mi (2,009.86 km) |
| Estepa to Statte | 1,204.78 mi (1,938.90 km) |
| Estepa to Stezzano | 945.98 mi (1,522.41 km) |
| Estepa to Strada | 953.95 mi (1,535.23 km) |
| Estepa to Stradella | 910.72 mi (1,465.67 km) |
| Estepa to Striano | 1,068.98 mi (1,720.36 km) |
| Estepa to Subiaco | 1,007.02 mi (1,620.64 km) |
| Estepa to Sulmona | 1,050.16 mi (1,690.07 km) |
