| Miami (Florida) to Guayama | 1,051.65 mi (1,692.47 km) |
| Tampa (Florida) to Guayama | 1,246.38 mi (2,005.85 km) |
| Atlanta (Georgia) to Guayama | 1,571.58 mi (2,529.22 km) |
| Washington (District of Columbia) to Guayama | 1,587.71 mi (2,555.18 km) |
| Baltimore (Maryland) to Guayama | 1,602.70 mi (2,579.30 km) |
| Philadelphia (Pennsylvania) to Guayama | 1,614.85 mi (2,598.85 km) |
| Brooklyn (New York) to Guayama | 1,634.61 mi (2,630.65 km) |
| New York (New York) to Guayama | 1,637.08 mi (2,634.63 km) |
| Queens (New York) to Guayama | 1,638.59 mi (2,637.06 km) |
| Boston (Massachusetts) to Guayama | 1,707.31 mi (2,747.65 km) |
| Detroit (Michigan) to Guayama | 1,959.77 mi (3,153.94 km) |
| Houston (Texas) to Guayama | 2,013.89 mi (3,241.05 km) |
| St. Louis (Missouri) to Guayama | 2,035.22 mi (3,275.38 km) |
| Chicago (Illinois) to Guayama | 2,082.04 mi (3,350.71 km) |
| Dallas (Texas) to Guayama | 2,158.60 mi (3,473.92 km) |
| Minneapolis (Minnesota) to Guayama | 2,433.80 mi (3,916.82 km) |
| Denver (Colorado) to Guayama | 2,754.78 mi (4,433.39 km) |
| Phoenix (Arizona) to Guayama | 3,028.39 mi (4,873.72 km) |
| Las Vegas (Nevada) to Guayama | 3,235.49 mi (5,207.02 km) |
| San Diego (California) to Guayama | 3,310.93 mi (5,328.43 km) |
| Riverside (California) to Guayama | 3,333.85 mi (5,365.32 km) |
| Los Angeles (California) to Guayama | 3,392.71 mi (5,460.04 km) |
| San Francisco (California) to Guayama | 3,641.97 mi (5,861.18 km) |
| Portland (Oregon) to Guayama | 3,731.98 mi (6,006.04 km) |
| Seattle (Washington) to Guayama | 3,747.15 mi (6,030.46 km) |
