| Festus to Des Plaines (Illinois) | 295.01 mi (474.77 km) |
| Festus to Desert Hot Springs (California) | 1,483.40 mi (2,387.30 km) |
| Festus to DeSoto (Texas) | 531.56 mi (855.46 km) |
| Festus to Destin (Florida) | 585.34 mi (942.01 km) |
| Festus to Destrehan (Louisiana) | 570.49 mi (918.12 km) |
| Festus to Detroit (Michigan) | 480.36 mi (773.07 km) |
| Festus to Diamond Bar (California) | 1,551.44 mi (2,496.79 km) |
| Festus to Diamond Springs (California) | 1,639.13 mi (2,637.92 km) |
| Festus to Dickinson (North Dakota) | 867.67 mi (1,396.38 km) |
| Festus to Dickinson (Texas) | 661.50 mi (1,064.57 km) |
| Festus to Dickson (Tennessee) | 224.20 mi (360.82 km) |
| Festus to Difficult Run (Virginia) | 706.71 mi (1,137.33 km) |
| Festus to Dinuba (California) | 1,589.25 mi (2,557.65 km) |
| Festus to Discovery Bay (California) | 1,688.72 mi (2,717.73 km) |
| Festus to Dix Hills (New York) | 925.81 mi (1,489.95 km) |
