| Festus to Elyria (Ohio) | 491.51 mi (791.01 km) |
| Festus to Emeryville (California) | 1,726.80 mi (2,779.01 km) |
| Festus to Emmaus (Pennsylvania) | 811.28 mi (1,305.63 km) |
| Festus to Emporia (Kansas) | 313.75 mi (504.94 km) |
| Festus to Encinitas (California) | 1,543.70 mi (2,484.34 km) |
| Festus to Endicott (New York) | 802.33 mi (1,291.23 km) |
| Festus to Endwell (New York) | 804.77 mi (1,295.16 km) |
| Festus to Englewood (Colorado) | 789.15 mi (1,270.02 km) |
| Festus to Englewood (Florida) | 906.78 mi (1,459.32 km) |
| Festus to Englewood (New Jersey) | 893.40 mi (1,437.78 km) |
| Festus to Englewood (Ohio) | 346.56 mi (557.74 km) |
| Festus to Enid (Oklahoma) | 428.53 mi (689.65 km) |
| Festus to Ennis (Texas) | 537.43 mi (864.91 km) |
| Festus to Ensley (Florida) | 560.75 mi (902.44 km) |
| Festus to Enterprise (Alabama) | 541.87 mi (872.05 km) |
