| Festus to Scottsboro (Alabama) | 346.03 mi (556.88 km) |
| Festus to Scottsdale (Arizona) | 1,237.06 mi (1,990.85 km) |
| Festus to Scranton (Pennsylvania) | 811.76 mi (1,306.41 km) |
| Festus to Seabrook (Maryland) | 733.39 mi (1,180.28 km) |
| Festus to Seabrook (Texas) | 653.00 mi (1,050.91 km) |
| Festus to Seaford (New York) | 916.88 mi (1,475.57 km) |
| Festus to Seagoville (Texas) | 516.68 mi (831.51 km) |
| Festus to Seal Beach (California) | 1,570.80 mi (2,527.96 km) |
| Festus to Searcy (Arkansas) | 218.42 mi (351.52 km) |
| Festus to Seaside (California) | 1,718.86 mi (2,766.24 km) |
| Festus to SeaTac (Washington) | 1,722.02 mi (2,771.33 km) |
| Festus to Seattle (Washington) | 1,725.36 mi (2,776.70 km) |
| Festus to Sebastian (Florida) | 921.23 mi (1,482.57 km) |
| Festus to Sebring (Florida) | 905.12 mi (1,456.66 km) |
| Festus to Secaucus (New Jersey) | 887.75 mi (1,428.70 km) |
