| Festus to St. Simons (Georgia) | 706.06 mi (1,136.29 km) |
| Festus to Stafford (Texas) | 662.88 mi (1,066.81 km) |
| Festus to Stallings (North Carolina) | 581.16 mi (935.29 km) |
| Festus to Stamford (Connecticut) | 916.63 mi (1,475.17 km) |
| Festus to Stanford (California) | 1,725.61 mi (2,777.10 km) |
| Festus to Stanton (California) | 1,565.53 mi (2,519.47 km) |
| Festus to Star (Idaho) | 1,406.04 mi (2,262.80 km) |
| Festus to Starkville (Mississippi) | 340.47 mi (547.94 km) |
| Festus to State College (Pennsylvania) | 691.70 mi (1,113.18 km) |
| Festus to Staten Island (New York) | 882.01 mi (1,419.46 km) |
| Festus to Statesboro (Georgia) | 629.16 mi (1,012.54 km) |
| Festus to Statesville (North Carolina) | 552.25 mi (888.76 km) |
| Festus to Staunton (Virginia) | 615.92 mi (991.22 km) |
| Festus to Steamboat Springs (Colorado) | 889.44 mi (1,431.42 km) |
| Festus to Steiner Ranch (Texas) | 690.17 mi (1,110.72 km) |
