| Festus to Storm Lake (Iowa) | 395.82 mi (637.00 km) |
| Festus to Storrs (Connecticut) | 990.28 mi (1,593.71 km) |
| Festus to Stoughton (Wisconsin) | 330.94 mi (532.60 km) |
| Festus to Stow (Ohio) | 518.72 mi (834.79 km) |
| Festus to Streamwood (Illinois) | 287.88 mi (463.30 km) |
| Festus to Streator (Illinois) | 217.59 mi (350.18 km) |
| Festus to Streetsboro (Ohio) | 524.56 mi (844.20 km) |
| Festus to Strongsville (Ohio) | 502.92 mi (809.38 km) |
| Festus to Stuart (Florida) | 962.65 mi (1,549.23 km) |
| Festus to Stuarts Draft (Virginia) | 618.05 mi (994.65 km) |
| Festus to Sturgis (Michigan) | 361.74 mi (582.17 km) |
| Festus to Suamico (Wisconsin) | 459.54 mi (739.56 km) |
| Festus to Sudley (Virginia) | 698.76 mi (1,124.55 km) |
| Festus to Suffern (New York) | 886.58 mi (1,426.82 km) |
| Festus to Suffolk (Virginia) | 761.81 mi (1,226.02 km) |
