| Florence to Seysses | 497.21 mi (800.18 km) |
| Florence to Sin-le-Noble | 594.45 mi (956.67 km) |
| Florence to Six-Fours-les-Plages | 276.50 mi (444.98 km) |
| Florence to Soissons | 539.92 mi (868.92 km) |
| Florence to Soisy-sous-Montmorency | 557.98 mi (897.99 km) |
| Florence to Sollies-Pont | 264.38 mi (425.48 km) |
| Florence to Somain | 589.15 mi (948.15 km) |
| Florence to Sorgues | 318.11 mi (511.95 km) |
| Florence to Sotteville-les-Rouen | 619.28 mi (996.64 km) |
| Florence to Soyaux | 557.59 mi (897.35 km) |
| Florence to Stains | 553.38 mi (890.58 km) |
| Florence to Stiring-Wendel | 427.64 mi (688.21 km) |
| Florence to Strasbourg | 372.34 mi (599.22 km) |
| Florence to Sucy-en-Brie | 540.86 mi (870.42 km) |
| Florence to Suresnes | 556.07 mi (894.90 km) |
