| Florence to Senftenberg | 550.28 mi (885.58 km) |
| Florence to Siegburg | 521.29 mi (838.94 km) |
| Florence to Siegen | 514.11 mi (827.38 km) |
| Florence to Sigmaringen | 313.80 mi (505.01 km) |
| Florence to Simbach am Inn | 321.88 mi (518.01 km) |
| Florence to Simmerath | 525.76 mi (846.13 km) |
| Florence to Sindelfingen | 357.96 mi (576.07 km) |
| Florence to Sinsheim | 394.91 mi (635.55 km) |
| Florence to Sinzheim | 374.94 mi (603.40 km) |
| Florence to Sinzig | 504.20 mi (811.43 km) |
| Florence to Soest | 558.28 mi (898.46 km) |
| Florence to Solingen | 546.61 mi (879.69 km) |
| Florence to Soltau | 639.78 mi (1,029.62 km) |
| Florence to Sommerda | 510.66 mi (821.83 km) |
| Florence to Sondershausen | 525.09 mi (845.06 km) |
