| Florence to Sala Consilina | 322.27 mi (518.65 km) |
| Florence to Salemi | 419.28 mi (674.76 km) |
| Florence to Salerno | 278.82 mi (448.72 km) |
| Florence to Salo | 131.21 mi (211.16 km) |
| Florence to Salsomaggiore Terme | 95.76 mi (154.11 km) |
| Florence to Saluzzo | 195.91 mi (315.29 km) |
| Florence to Salzano | 128.90 mi (207.45 km) |
| Florence to Samarate | 176.01 mi (283.26 km) |
| Florence to San Benedetto del Tronto | 143.74 mi (231.33 km) |
| Florence to San Biagio di Callalta | 143.43 mi (230.83 km) |
| Florence to San Bonifacio | 112.53 mi (181.11 km) |
| Florence to San Casciano in Val di Pesa | 8.62 mi (13.87 km) |
| Florence to San Cataldo | 457.36 mi (736.04 km) |
| Florence to San Cesareo | 156.14 mi (251.29 km) |
| Florence to San Dona di Piave | 143.61 mi (231.12 km) |
