| Florence to Selvazzano Dentro | 114.37 mi (184.07 km) |
| Florence to Senago | 162.87 mi (262.11 km) |
| Florence to Senigallia | 98.12 mi (157.91 km) |
| Florence to Seravezza | 53.23 mi (85.67 km) |
| Florence to Seregno | 164.37 mi (264.53 km) |
| Florence to Seriate | 152.19 mi (244.92 km) |
| Florence to Sermoneta | 176.84 mi (284.60 km) |
| Florence to Serramanna | 323.69 mi (520.93 km) |
| Florence to Serravalle Pistoiese | 22.78 mi (36.66 km) |
| Florence to Sessa Aurunca | 222.18 mi (357.57 km) |
| Florence to Sesto Calende | 186.83 mi (300.67 km) |
| Florence to Sesto Fiorentino | 5.06 mi (8.14 km) |
| Florence to Sesto San Giovanni | 157.11 mi (252.84 km) |
| Florence to Sestri Levante | 98.75 mi (158.92 km) |
| Florence to Sestu | 328.57 mi (528.78 km) |
