| Florence to Somma Lombardo | 182.11 mi (293.08 km) |
| Florence to Somma Vesuviana | 257.94 mi (415.11 km) |
| Florence to Sommacampagna | 114.27 mi (183.90 km) |
| Florence to Sona | 116.68 mi (187.77 km) |
| Florence to Sondrio | 178.98 mi (288.04 km) |
| Florence to Sora | 185.79 mi (299.00 km) |
| Florence to Sorbolo | 84.27 mi (135.63 km) |
| Florence to Soresina | 125.27 mi (201.61 km) |
| Florence to Sorisole | 156.83 mi (252.40 km) |
| Florence to Sorrento | 269.53 mi (433.76 km) |
| Florence to Sorso | 246.79 mi (397.17 km) |
| Florence to Sortino | 497.55 mi (800.74 km) |
| Florence to Soverato Marina | 446.25 mi (718.16 km) |
| Florence to Sovicille | 33.74 mi (54.30 km) |
| Florence to Spello | 89.41 mi (143.88 km) |
