| Florence to Santiago do Cacem | 1,112.01 mi (1,789.60 km) |
| Florence to Santo Andre | 1,113.37 mi (1,791.80 km) |
| Florence to Santo Tirso | 1,015.29 mi (1,633.94 km) |
| Florence to Sao Bras de Alportel | 1,101.76 mi (1,773.11 km) |
| Florence to Sao Felix da Marinha | 1,029.00 mi (1,656.02 km) |
| Florence to Sao Joao da Madeira | 1,025.17 mi (1,649.84 km) |
| Florence to Sao Joao de Ver | 1,027.07 mi (1,652.91 km) |
| Florence to Sao Mamede de Infesta | 1,024.52 mi (1,648.81 km) |
| Florence to Sao Pedro do Sul | 1,007.32 mi (1,621.13 km) |
| Florence to Satao | 991.13 mi (1,595.07 km) |
| Florence to Seia | 996.63 mi (1,603.92 km) |
| Florence to Senhora da Hora | 1,027.34 mi (1,653.35 km) |
| Florence to Serpa | 1,061.25 mi (1,707.91 km) |
| Florence to Serta | 1,031.48 mi (1,660.00 km) |
| Florence to Sesimbra | 1,118.26 mi (1,799.67 km) |
