| Florida to Enterprise (Nevada) | 3,191.45 mi (5,136.15 km) |
| Florida to Enumclaw (Washington) | 3,685.44 mi (5,931.14 km) |
| Florida to Ephrata (Pennsylvania) | 1,612.54 mi (2,595.13 km) |
| Florida to Erie (Colorado) | 2,729.98 mi (4,393.48 km) |
| Florida to Erie (Pennsylvania) | 1,823.21 mi (2,934.17 km) |
| Florida to Erlanger (Kentucky) | 1,789.33 mi (2,879.64 km) |
| Florida to Escanaba (Michigan) | 2,227.05 mi (3,584.09 km) |
| Florida to Escondido (California) | 3,271.07 mi (5,264.27 km) |
| Florida to Española (New Mexico) | 2,691.94 mi (4,332.26 km) |
| Florida to Essex (Maryland) | 1,562.97 mi (2,515.35 km) |
| Florida to Essex Junction (Vermont) | 1,844.49 mi (2,968.42 km) |
| Florida to Estelle (Louisiana) | 1,678.22 mi (2,700.83 km) |
| Florida to Estero (Florida) | 1,119.94 mi (1,802.38 km) |
| Florida to Euclid (Ohio) | 1,831.23 mi (2,947.08 km) |
| Florida to Eufaula (Alabama) | 1,488.39 mi (2,395.34 km) |
