| Florida to Olympia Heights (Florida) | 1,017.35 mi (1,637.26 km) |
| Florida to Omaha (Nebraska) | 2,351.16 mi (3,783.83 km) |
| Florida to On Top of the World Designated Place (Florida) | 1,238.74 mi (1,993.56 km) |
| Florida to Onalaska (Wisconsin) | 2,269.72 mi (3,652.77 km) |
| Florida to Oneida (New York) | 1,788.33 mi (2,878.04 km) |
| Florida to Oneonta (New York) | 1,737.70 mi (2,796.55 km) |
| Florida to Ontario (California) | 3,307.55 mi (5,322.99 km) |
| Florida to Ontario (Oregon) | 3,397.37 mi (5,467.55 km) |
| Florida to Opa-locka (Florida) | 1,018.36 mi (1,638.89 km) |
| Florida to Opelika (Alabama) | 1,529.04 mi (2,460.76 km) |
| Florida to Opelousas (Louisiana) | 1,805.44 mi (2,905.57 km) |
| Florida to Orange (California) | 3,318.30 mi (5,340.28 km) |
| Florida to Orange (Texas) | 1,889.50 mi (3,040.86 km) |
| Florida to Orange City (Florida) | 1,182.17 mi (1,902.51 km) |
| Florida to Orangeburg (South Carolina) | 1,369.00 mi (2,203.20 km) |
