| Florida to Sanford (Maine) | 1,748.67 mi (2,814.22 km) |
| Florida to Sanford (North Carolina) | 1,412.52 mi (2,273.23 km) |
| Florida to Sanger (California) | 3,436.62 mi (5,530.70 km) |
| Florida to Santa Ana (California) | 3,321.31 mi (5,345.13 km) |
| Florida to Santa Barbara (California) | 3,430.22 mi (5,520.41 km) |
| Florida to Santa Clara (California) | 3,573.73 mi (5,751.36 km) |
| Florida to Santa Clara (Oregon) | 3,697.28 mi (5,950.19 km) |
| Florida to Santa Clarita (California) | 3,360.68 mi (5,408.49 km) |
| Florida to Santa Cruz (California) | 3,574.86 mi (5,753.18 km) |
| Florida to Santa Fe (New Mexico) | 2,680.73 mi (4,314.22 km) |
| Florida to Santa Fe (Texas) | 1,950.43 mi (3,138.92 km) |
| Florida to Santa Fe Springs (California) | 3,332.87 mi (5,363.73 km) |
| Florida to Santa Maria (California) | 3,473.99 mi (5,590.84 km) |
| Florida to Santa Monica (California) | 3,357.31 mi (5,403.07 km) |
| Florida to Santa Paula (California) | 3,392.60 mi (5,459.87 km) |
