| Florida to Santa Rosa (California) | 3,621.31 mi (5,827.93 km) |
| Florida to Santaquin (Utah) | 3,066.99 mi (4,935.85 km) |
| Florida to Santee (California) | 3,264.33 mi (5,253.43 km) |
| Florida to Sapulpa (Oklahoma) | 2,172.47 mi (3,496.25 km) |
| Florida to Saraland (Alabama) | 1,599.73 mi (2,574.52 km) |
| Florida to Sarasota (Florida) | 1,189.83 mi (1,914.85 km) |
| Florida to Sarasota Springs (Florida) | 1,185.14 mi (1,907.30 km) |
| Florida to Saratoga (California) | 3,576.27 mi (5,755.46 km) |
| Florida to Saratoga Springs (New York) | 1,758.12 mi (2,829.42 km) |
| Florida to Saratoga Springs (Utah) | 3,080.16 mi (4,957.04 km) |
| Florida to Sartell (Minnesota) | 2,459.57 mi (3,958.30 km) |
| Florida to Satellite Beach (Florida) | 1,118.20 mi (1,799.57 km) |
| Florida to Sauk Rapids (Minnesota) | 2,456.20 mi (3,952.87 km) |
| Florida to Sault Ste. Marie (Michigan) | 2,191.39 mi (3,526.71 km) |
| Florida to Savage (Minnesota) | 2,388.91 mi (3,844.57 km) |
