| Florida to Scottsboro (Alabama) | 1,642.31 mi (2,643.05 km) |
| Florida to Scottsdale (Arizona) | 2,977.80 mi (4,792.31 km) |
| Florida to Scranton (Pennsylvania) | 1,680.31 mi (2,704.19 km) |
| Florida to Seabrook (Maryland) | 1,552.34 mi (2,498.25 km) |
| Florida to Seabrook (Texas) | 1,949.71 mi (3,137.76 km) |
| Florida to Seaford (New York) | 1,595.00 mi (2,566.91 km) |
| Florida to Seagoville (Texas) | 2,103.54 mi (3,385.32 km) |
| Florida to Seal Beach (California) | 3,332.26 mi (5,362.76 km) |
| Florida to Searcy (Arkansas) | 1,931.59 mi (3,108.59 km) |
| Florida to Seaside (California) | 3,560.80 mi (5,730.56 km) |
| Florida to SeaTac (Washington) | 3,703.31 mi (5,959.90 km) |
| Florida to Seattle (Washington) | 3,707.23 mi (5,966.21 km) |
| Florida to Sebastian (Florida) | 1,096.88 mi (1,765.25 km) |
| Florida to Sebring (Florida) | 1,136.16 mi (1,828.47 km) |
| Florida to Secaucus (New Jersey) | 1,611.55 mi (2,593.54 km) |
