| Florida to Smyrna (Delaware) | 1,544.17 mi (2,485.10 km) |
| Florida to Smyrna (Georgia) | 1,540.34 mi (2,478.94 km) |
| Florida to Smyrna (Tennessee) | 1,720.81 mi (2,769.37 km) |
| Florida to Snellville (Georgia) | 1,517.48 mi (2,442.15 km) |
| Florida to Snoqualmie (Washington) | 3,683.85 mi (5,928.59 km) |
| Florida to Snyder (Texas) | 2,345.61 mi (3,774.89 km) |
| Florida to Socastee (South Carolina) | 1,308.25 mi (2,105.43 km) |
| Florida to Socorro (Texas) | 2,632.28 mi (4,236.24 km) |
| Florida to Soddy-Daisy (Tennessee) | 1,631.06 mi (2,624.94 km) |
| Florida to Solana Beach (California) | 3,280.89 mi (5,280.08 km) |
| Florida to Soledad (California) | 3,533.29 mi (5,686.28 km) |
| Florida to Solon (Ohio) | 1,817.22 mi (2,924.54 km) |
| Florida to Somers Point (New Jersey) | 1,525.68 mi (2,455.34 km) |
| Florida to Somerset (Kentucky) | 1,693.91 mi (2,726.09 km) |
| Florida to Somerset (New Jersey) | 1,601.09 mi (2,576.70 km) |
