| Fort Myers to Des Plaines (Illinois) | 1,119.20 mi (1,801.17 km) |
| Fort Myers to Desert Hot Springs (California) | 2,121.32 mi (3,413.94 km) |
| Fort Myers to DeSoto (Texas) | 991.76 mi (1,596.09 km) |
| Fort Myers to Destin (Florida) | 383.87 mi (617.77 km) |
| Fort Myers to Destrehan (Louisiana) | 568.24 mi (914.49 km) |
| Fort Myers to Detroit (Michigan) | 1,091.56 mi (1,756.69 km) |
| Fort Myers to Diamond Bar (California) | 2,194.31 mi (3,531.40 km) |
| Fort Myers to Diamond Springs (California) | 2,396.38 mi (3,856.60 km) |
| Fort Myers to Dickinson (North Dakota) | 1,806.99 mi (2,908.06 km) |
| Fort Myers to Dickinson (Texas) | 829.66 mi (1,335.21 km) |
| Fort Myers to Dickson (Tennessee) | 729.39 mi (1,173.84 km) |
| Fort Myers to Difficult Run (Virginia) | 887.36 mi (1,428.07 km) |
| Fort Myers to Dinuba (California) | 2,298.78 mi (3,699.53 km) |
| Fort Myers to Discovery Bay (California) | 2,429.94 mi (3,910.62 km) |
| Fort Myers to Dix Hills (New York) | 1,093.48 mi (1,759.78 km) |
