| Fort Myers to Elyria (Ohio) | 1,019.70 mi (1,641.05 km) |
| Fort Myers to Emeryville (California) | 2,467.02 mi (3,970.29 km) |
| Fort Myers to Emmaus (Pennsylvania) | 1,027.51 mi (1,653.61 km) |
| Fort Myers to Emporia (Kansas) | 1,164.75 mi (1,874.48 km) |
| Fort Myers to Encinitas (California) | 2,158.94 mi (3,474.48 km) |
| Fort Myers to Endicott (New York) | 1,118.18 mi (1,799.53 km) |
| Fort Myers to Endwell (New York) | 1,120.21 mi (1,802.80 km) |
| Fort Myers to Englewood (Colorado) | 1,606.66 mi (2,585.67 km) |
| Fort Myers to Englewood (Florida) | 40.37 mi (64.97 km) |
| Fort Myers to Englewood (New Jersey) | 1,083.31 mi (1,743.41 km) |
| Fort Myers to Englewood (Ohio) | 926.15 mi (1,490.49 km) |
| Fort Myers to Enid (Oklahoma) | 1,159.17 mi (1,865.51 km) |
| Fort Myers to Ennis (Texas) | 972.68 mi (1,565.37 km) |
| Fort Myers to Ensley (Florida) | 426.43 mi (686.27 km) |
| Fort Myers to Enterprise (Alabama) | 405.81 mi (653.09 km) |
