| Fort Myers to Orangevale (California) | 2,416.71 mi (3,889.31 km) |
| Fort Myers to Orchards (Washington) | 2,586.32 mi (4,162.28 km) |
| Fort Myers to Orcutt (California) | 2,346.16 mi (3,775.78 km) |
| Fort Myers to Oregon (Ohio) | 1,042.66 mi (1,677.99 km) |
| Fort Myers to Oregon (Wisconsin) | 1,204.24 mi (1,938.04 km) |
| Fort Myers to Oregon City (Oregon) | 2,582.50 mi (4,156.14 km) |
| Fort Myers to Orem (Utah) | 1,950.44 mi (3,138.93 km) |
| Fort Myers to Orinda (California) | 2,461.16 mi (3,960.85 km) |
| Fort Myers to Orland Park (Illinois) | 1,090.79 mi (1,755.45 km) |
| Fort Myers to Orlando (Florida) | 131.88 mi (212.23 km) |
| Fort Myers to Ormond Beach (Florida) | 190.37 mi (306.38 km) |
| Fort Myers to Oro Valley (Arizona) | 1,791.66 mi (2,883.39 km) |
| Fort Myers to Oroville (California) | 2,443.32 mi (3,932.15 km) |
| Fort Myers to Oshkosh (Wisconsin) | 1,259.79 mi (2,027.43 km) |
| Fort Myers to Oskaloosa (Iowa) | 1,185.87 mi (1,908.47 km) |
