| Fort Myers to Sanford (Maine) | 1,316.56 mi (2,118.80 km) |
| Fort Myers to Sanford (North Carolina) | 632.45 mi (1,017.83 km) |
| Fort Myers to Sanger (California) | 2,308.74 mi (3,715.55 km) |
| Fort Myers to Santa Ana (California) | 2,197.01 mi (3,535.75 km) |
| Fort Myers to Santa Barbara (California) | 2,304.64 mi (3,708.96 km) |
| Fort Myers to Santa Clara (California) | 2,445.89 mi (3,936.27 km) |
| Fort Myers to Santa Clara (Oregon) | 2,586.41 mi (4,162.43 km) |
| Fort Myers to Santa Clarita (California) | 2,234.97 mi (3,596.84 km) |
| Fort Myers to Santa Cruz (California) | 2,446.97 mi (3,938.02 km) |
| Fort Myers to Santa Fe (New Mexico) | 1,553.44 mi (2,500.03 km) |
| Fort Myers to Santa Fe (Texas) | 831.30 mi (1,337.85 km) |
| Fort Myers to Santa Fe Springs (California) | 2,208.12 mi (3,553.63 km) |
| Fort Myers to Santa Maria (California) | 2,347.60 mi (3,778.10 km) |
| Fort Myers to Santa Monica (California) | 2,232.42 mi (3,592.73 km) |
| Fort Myers to Santa Paula (California) | 2,267.09 mi (3,648.53 km) |
