| Fort Myers to Seymour (Tennessee) | 649.83 mi (1,045.80 km) |
| Fort Myers to Shady Hills (Florida) | 130.90 mi (210.67 km) |
| Fort Myers to Shafter (California) | 2,280.43 mi (3,669.99 km) |
| Fort Myers to Shaker Heights (Ohio) | 1,026.51 mi (1,652.00 km) |
| Fort Myers to Shakopee (Minnesota) | 1,411.01 mi (2,270.80 km) |
| Fort Myers to Sharon (Pennsylvania) | 1,012.61 mi (1,629.64 km) |
| Fort Myers to Sharonville (Ohio) | 887.48 mi (1,428.27 km) |
| Fort Myers to Shasta Lake (California) | 2,499.32 mi (4,022.26 km) |
| Fort Myers to Shawnee (Kansas) | 1,138.30 mi (1,831.92 km) |
| Fort Myers to Shawnee (Oklahoma) | 1,078.56 mi (1,735.78 km) |
| Fort Myers to Sheboygan (Wisconsin) | 1,228.13 mi (1,976.49 km) |
| Fort Myers to Shelby (North Carolina) | 599.35 mi (964.55 km) |
| Fort Myers to Shelbyville (Indiana) | 920.94 mi (1,482.11 km) |
| Fort Myers to Shelbyville (Kentucky) | 824.61 mi (1,327.08 km) |
| Fort Myers to Shelbyville (Tennessee) | 671.48 mi (1,080.64 km) |
