| Fort Myers to Silver Firs (Washington) | 2,615.54 mi (4,209.30 km) |
| Fort Myers to Silver Spring (Maryland) | 899.65 mi (1,447.85 km) |
| Fort Myers to Silver Springs Shores (Florida) | 172.63 mi (277.82 km) |
| Fort Myers to Silverdale (Washington) | 2,634.47 mi (4,239.77 km) |
| Fort Myers to Silverton (Oregon) | 2,585.03 mi (4,160.21 km) |
| Fort Myers to Simi Valley (California) | 2,248.69 mi (3,618.92 km) |
| Fort Myers to Simpsonville (South Carolina) | 560.87 mi (902.63 km) |
| Fort Myers to Sioux City (Iowa) | 1,370.34 mi (2,205.35 km) |
| Fort Myers to Sioux Falls (South Dakota) | 1,436.11 mi (2,311.20 km) |
| Fort Myers to Skokie (Illinois) | 1,116.53 mi (1,796.88 km) |
| Fort Myers to Sleepy Hollow (New York) | 1,098.14 mi (1,767.29 km) |
| Fort Myers to Slidell (Louisiana) | 545.36 mi (877.68 km) |
| Fort Myers to Smithfield (North Carolina) | 647.98 mi (1,042.82 km) |
| Fort Myers to Smithfield (Utah) | 1,994.64 mi (3,210.07 km) |
| Fort Myers to Smithville (Missouri) | 1,148.17 mi (1,847.81 km) |
