| Fort Myers to Smyrna (Delaware) | 946.42 mi (1,523.12 km) |
| Fort Myers to Smyrna (Georgia) | 525.50 mi (845.71 km) |
| Fort Myers to Smyrna (Tennessee) | 702.70 mi (1,130.89 km) |
| Fort Myers to Snellville (Georgia) | 516.53 mi (831.27 km) |
| Fort Myers to Snoqualmie (Washington) | 2,594.32 mi (4,175.15 km) |
| Fort Myers to Snyder (Texas) | 1,218.28 mi (1,960.63 km) |
| Fort Myers to Socastee (South Carolina) | 516.54 mi (831.29 km) |
| Fort Myers to Socorro (Texas) | 1,511.19 mi (2,432.03 km) |
| Fort Myers to Soddy-Daisy (Tennessee) | 628.72 mi (1,011.83 km) |
| Fort Myers to Solana Beach (California) | 2,158.58 mi (3,473.89 km) |
| Fort Myers to Soledad (California) | 2,405.51 mi (3,871.30 km) |
| Fort Myers to Solon (Ohio) | 1,020.55 mi (1,642.42 km) |
| Fort Myers to Somers Point (New Jersey) | 971.23 mi (1,563.05 km) |
| Fort Myers to Somerset (Kentucky) | 741.07 mi (1,192.64 km) |
| Fort Myers to Somerset (New Jersey) | 1,047.30 mi (1,685.47 km) |
