| Fort Myers to Storm Lake (Iowa) | 1,339.07 mi (2,155.02 km) |
| Fort Myers to Storrs (Connecticut) | 1,181.72 mi (1,901.79 km) |
| Fort Myers to Stoughton (Wisconsin) | 1,200.86 mi (1,932.60 km) |
| Fort Myers to Stow (Ohio) | 1,006.05 mi (1,619.08 km) |
| Fort Myers to Streamwood (Illinois) | 1,123.24 mi (1,807.67 km) |
| Fort Myers to Streator (Illinois) | 1,078.68 mi (1,735.97 km) |
| Fort Myers to Streetsboro (Ohio) | 1,010.53 mi (1,626.30 km) |
| Fort Myers to Strongsville (Ohio) | 1,015.22 mi (1,633.83 km) |
| Fort Myers to Stuart (Florida) | 105.51 mi (169.81 km) |
| Fort Myers to Stuarts Draft (Virginia) | 804.23 mi (1,294.28 km) |
| Fort Myers to Sturgis (Michigan) | 1,068.39 mi (1,719.41 km) |
| Fort Myers to Suamico (Wisconsin) | 1,292.13 mi (2,079.48 km) |
| Fort Myers to Sudley (Virginia) | 877.39 mi (1,412.03 km) |
| Fort Myers to Suffern (New York) | 1,093.13 mi (1,759.22 km) |
| Fort Myers to Suffolk (Virginia) | 759.81 mi (1,222.80 km) |
