| Fort Myers to Superior (Colorado) | 1,623.50 mi (2,612.78 km) |
| Fort Myers to Superior (Wisconsin) | 1,495.86 mi (2,407.35 km) |
| Fort Myers to Surprise (Arizona) | 1,885.75 mi (3,034.82 km) |
| Fort Myers to Susanville (California) | 2,404.99 mi (3,870.45 km) |
| Fort Myers to Sussex (Wisconsin) | 1,196.28 mi (1,925.23 km) |
| Fort Myers to Suwanee (Georgia) | 530.48 mi (853.72 km) |
| Fort Myers to Swansea (Illinois) | 950.31 mi (1,529.38 km) |
| Fort Myers to Sweetwater (Florida) | 107.25 mi (172.61 km) |
| Fort Myers to Sweetwater (Texas) | 1,185.64 mi (1,908.10 km) |
| Fort Myers to Sycamore (Illinois) | 1,131.08 mi (1,820.30 km) |
| Fort Myers to Sylacauga (Alabama) | 524.98 mi (844.88 km) |
| Fort Myers to Sylvania (Ohio) | 1,048.10 mi (1,686.76 km) |
| Fort Myers to Syosset (New York) | 1,090.10 mi (1,754.35 km) |
| Fort Myers to Syracuse (New York) | 1,178.79 mi (1,897.08 km) |
| Fort Myers to Syracuse (Utah) | 1,987.45 mi (3,198.49 km) |
