| Frodsham to Spello | 1,001.44 mi (1,611.66 km) |
| Frodsham to Spilamberto | 866.61 mi (1,394.67 km) |
| Frodsham to Spilimbergo | 852.40 mi (1,371.80 km) |
| Frodsham to Spinea | 856.57 mi (1,378.51 km) |
| Frodsham to Spoleto | 1,014.33 mi (1,632.40 km) |
| Frodsham to Spoltore | 1,077.45 mi (1,733.99 km) |
| Frodsham to Spresiano | 845.81 mi (1,361.19 km) |
| Frodsham to Squinzano | 1,315.06 mi (2,116.39 km) |
| Frodsham to Statte | 1,279.18 mi (2,058.65 km) |
| Frodsham to Stezzano | 764.70 mi (1,230.66 km) |
| Frodsham to Strada | 926.60 mi (1,491.21 km) |
| Frodsham to Stradella | 783.34 mi (1,260.66 km) |
| Frodsham to Striano | 1,179.60 mi (1,898.38 km) |
| Frodsham to Subiaco | 1,072.12 mi (1,725.42 km) |
| Frodsham to Sulmona | 1,092.17 mi (1,757.68 km) |
