| Goes to Santander | 660.45 mi (1,062.89 km) |
| Goes to Santany | 839.98 mi (1,351.82 km) |
| Goes to Santiago de Compostela | 831.75 mi (1,338.57 km) |
| Goes to Santiago del Teide | 1,928.02 mi (3,102.85 km) |
| Goes to Santiponce | 1,085.79 mi (1,747.40 km) |
| Goes to Santomera | 958.93 mi (1,543.24 km) |
| Goes to Santona | 653.14 mi (1,051.13 km) |
| Goes to Santurce-Antiguo | 649.82 mi (1,045.79 km) |
| Goes to Sarria | 801.13 mi (1,289.30 km) |
| Goes to Sauzal | 1,905.99 mi (3,067.40 km) |
| Goes to Sedavi | 859.03 mi (1,382.48 km) |
| Goes to Segorbe | 831.64 mi (1,338.40 km) |
| Goes to Segovia | 822.16 mi (1,323.13 km) |
| Goes to Senmanat | 688.40 mi (1,107.87 km) |
| Goes to Sesena | 866.86 mi (1,395.07 km) |
