| Grammichele to Settimo Torinese | 652.88 mi (1,050.71 km) |
| Grammichele to Seveso | 647.91 mi (1,042.71 km) |
| Grammichele to Sezze | 307.72 mi (495.22 km) |
| Grammichele to Siano | 247.91 mi (398.98 km) |
| Grammichele to Siena | 456.19 mi (734.17 km) |
| Grammichele to Signa | 490.28 mi (789.03 km) |
| Grammichele to Silea | 595.53 mi (958.42 km) |
| Grammichele to Silvi Paese | 369.66 mi (594.91 km) |
| Grammichele to Sinalunga | 442.00 mi (711.33 km) |
| Grammichele to Siniscola | 352.67 mi (567.57 km) |
| Grammichele to Sinnai | 328.10 mi (528.03 km) |
| Grammichele to Siracusa | 37.24 mi (59.94 km) |
| Grammichele to Solaro | 647.40 mi (1,041.88 km) |
| Grammichele to Soliera | 554.54 mi (892.45 km) |
| Grammichele to Solofra | 250.28 mi (402.79 km) |
