| Grande-Synthe to Sin-le-Noble | 57.27 mi (92.17 km) |
| Grande-Synthe to Six-Fours-les-Plages | 571.08 mi (919.06 km) |
| Grande-Synthe to Soissons | 121.47 mi (195.49 km) |
| Grande-Synthe to Soisy-sous-Montmorency | 139.99 mi (225.29 km) |
| Grande-Synthe to Sollies-Pont | 568.26 mi (914.52 km) |
| Grande-Synthe to Somain | 62.35 mi (100.35 km) |
| Grande-Synthe to Sorgues | 498.59 mi (802.41 km) |
| Grande-Synthe to Sotteville-les-Rouen | 123.16 mi (198.20 km) |
| Grande-Synthe to Soyaux | 383.62 mi (617.38 km) |
| Grande-Synthe to Stains | 142.65 mi (229.57 km) |
| Grande-Synthe to Stiring-Wendel | 240.22 mi (386.59 km) |
| Grande-Synthe to Strasbourg | 295.06 mi (474.85 km) |
| Grande-Synthe to Sucy-en-Brie | 155.37 mi (250.04 km) |
| Grande-Synthe to Suresnes | 148.17 mi (238.46 km) |
| Grande-Synthe to Talant | 281.85 mi (453.59 km) |
