| Grande-Synthe to Sala Consilina | 971.39 mi (1,563.30 km) |
| Grande-Synthe to Salemi | 1,046.35 mi (1,683.94 km) |
| Grande-Synthe to Salerno | 929.71 mi (1,496.23 km) |
| Grande-Synthe to Salo | 531.36 mi (855.15 km) |
| Grande-Synthe to Salsomaggiore Terme | 556.02 mi (894.83 km) |
| Grande-Synthe to Saluzzo | 501.23 mi (806.65 km) |
| Grande-Synthe to Salzano | 588.26 mi (946.72 km) |
| Grande-Synthe to Samarate | 476.83 mi (767.38 km) |
| Grande-Synthe to San Benedetto del Tronto | 778.25 mi (1,252.48 km) |
| Grande-Synthe to San Biagio di Callalta | 590.43 mi (950.20 km) |
| Grande-Synthe to San Bonifacio | 566.22 mi (911.25 km) |
| Grande-Synthe to San Casciano in Val di Pesa | 655.85 mi (1,055.48 km) |
| Grande-Synthe to San Cataldo | 1,096.19 mi (1,764.15 km) |
| Grande-Synthe to San Cesareo | 806.95 mi (1,298.65 km) |
| Grande-Synthe to San Dona di Piave | 599.61 mi (964.97 km) |
