| Grande-Synthe to Santeramo in Colle | 987.36 mi (1,589.00 km) |
| Grande-Synthe to Santo Stefano di Magra | 590.88 mi (950.93 km) |
| Grande-Synthe to Santo Stino di Livenza | 599.15 mi (964.25 km) |
| Grande-Synthe to Sarezzo | 518.04 mi (833.70 km) |
| Grande-Synthe to Sarno | 917.71 mi (1,476.91 km) |
| Grande-Synthe to Saronno | 483.67 mi (778.40 km) |
| Grande-Synthe to Sarzana | 594.93 mi (957.44 km) |
| Grande-Synthe to Sassari | 771.19 mi (1,241.10 km) |
| Grande-Synthe to Sasso Marconi | 617.09 mi (993.11 km) |
| Grande-Synthe to Sassuolo | 594.59 mi (956.90 km) |
| Grande-Synthe to Sava | 1,035.41 mi (1,666.33 km) |
| Grande-Synthe to Saviano | 909.05 mi (1,462.97 km) |
| Grande-Synthe to Savigliano | 504.13 mi (811.33 km) |
| Grande-Synthe to Savignano sul Panaro | 605.89 mi (975.09 km) |
| Grande-Synthe to Savignano sul Rubicone | 669.97 mi (1,078.21 km) |
