| Grande-Synthe to Savona | 544.85 mi (876.85 km) |
| Grande-Synthe to Scafati | 918.48 mi (1,478.14 km) |
| Grande-Synthe to Scalea | 1,010.19 mi (1,625.74 km) |
| Grande-Synthe to Scandiano | 589.40 mi (948.54 km) |
| Grande-Synthe to Scandicci | 650.52 mi (1,046.91 km) |
| Grande-Synthe to Schio | 553.32 mi (890.48 km) |
| Grande-Synthe to Sciacca | 1,072.38 mi (1,725.83 km) |
| Grande-Synthe to Scicli | 1,156.97 mi (1,861.96 km) |
| Grande-Synthe to Scordia | 1,129.97 mi (1,818.50 km) |
| Grande-Synthe to Scorze | 586.15 mi (943.32 km) |
| Grande-Synthe to Sedico | 560.62 mi (902.23 km) |
| Grande-Synthe to Sedriano | 489.51 mi (787.79 km) |
| Grande-Synthe to Segni | 820.87 mi (1,321.07 km) |
| Grande-Synthe to Segrate | 498.70 mi (802.58 km) |
| Grande-Synthe to Selargius | 877.68 mi (1,412.49 km) |
