| Grande-Synthe to Somma Lombardo | 470.74 mi (757.58 km) |
| Grande-Synthe to Somma Vesuviana | 909.10 mi (1,463.06 km) |
| Grande-Synthe to Sommacampagna | 551.91 mi (888.21 km) |
| Grande-Synthe to Sona | 549.66 mi (884.59 km) |
| Grande-Synthe to Sondrio | 480.80 mi (773.78 km) |
| Grande-Synthe to Sora | 836.89 mi (1,346.84 km) |
| Grande-Synthe to Sorbolo | 568.36 mi (914.69 km) |
| Grande-Synthe to Soresina | 526.58 mi (847.45 km) |
| Grande-Synthe to Sorisole | 496.32 mi (798.75 km) |
| Grande-Synthe to Sorrento | 921.02 mi (1,482.23 km) |
| Grande-Synthe to Sorso | 766.90 mi (1,234.20 km) |
| Grande-Synthe to Sortino | 1,142.92 mi (1,839.35 km) |
| Grande-Synthe to Soverato Marina | 1,097.35 mi (1,766.01 km) |
| Grande-Synthe to Sovicille | 678.24 mi (1,091.52 km) |
| Grande-Synthe to Spello | 737.63 mi (1,187.09 km) |
