| Grande-Synthe to Spilamberto | 602.69 mi (969.94 km) |
| Grande-Synthe to Spilimbergo | 589.03 mi (947.96 km) |
| Grande-Synthe to Spinea | 591.72 mi (952.28 km) |
| Grande-Synthe to Spoleto | 750.80 mi (1,208.30 km) |
| Grande-Synthe to Spoltore | 812.87 mi (1,308.20 km) |
| Grande-Synthe to Spresiano | 581.25 mi (935.43 km) |
| Grande-Synthe to Squinzano | 1,050.09 mi (1,689.96 km) |
| Grande-Synthe to Statte | 1,014.25 mi (1,632.28 km) |
| Grande-Synthe to Stezzano | 500.81 mi (805.97 km) |
| Grande-Synthe to Strada | 663.81 mi (1,068.31 km) |
| Grande-Synthe to Stradella | 521.39 mi (839.10 km) |
| Grande-Synthe to Striano | 916.18 mi (1,474.46 km) |
| Grande-Synthe to Subiaco | 809.20 mi (1,302.28 km) |
| Grande-Synthe to Sulmona | 828.11 mi (1,332.71 km) |
| Grande-Synthe to Surbo | 1,054.69 mi (1,697.36 km) |
