| Grande-Synthe to Santander | 594.74 mi (957.15 km) |
| Grande-Synthe to Santany | 806.60 mi (1,298.09 km) |
| Grande-Synthe to Santiago de Compostela | 758.57 mi (1,220.80 km) |
| Grande-Synthe to Santiago del Teide | 1,858.02 mi (2,990.20 km) |
| Grande-Synthe to Santiponce | 1,023.59 mi (1,647.31 km) |
| Grande-Synthe to Santomera | 909.76 mi (1,464.11 km) |
| Grande-Synthe to Santona | 588.46 mi (947.03 km) |
| Grande-Synthe to Santurce-Antiguo | 586.66 mi (944.13 km) |
| Grande-Synthe to Sarria | 729.44 mi (1,173.92 km) |
| Grande-Synthe to Sauzal | 1,836.23 mi (2,955.13 km) |
| Grande-Synthe to Sedavi | 811.04 mi (1,305.24 km) |
| Grande-Synthe to Segorbe | 782.86 mi (1,259.89 km) |
| Grande-Synthe to Segovia | 760.04 mi (1,223.16 km) |
| Grande-Synthe to Senmanat | 649.89 mi (1,045.90 km) |
| Grande-Synthe to Sesena | 807.12 mi (1,298.94 km) |
