| Grande-Synthe to Sestao | 587.38 mi (945.30 km) |
| Grande-Synthe to Sevilla | 1,035.17 mi (1,665.95 km) |
| Grande-Synthe to Sevilla La Nueva | 797.10 mi (1,282.82 km) |
| Grande-Synthe to Silla | 815.70 mi (1,312.74 km) |
| Grande-Synthe to Silleda | 758.61 mi (1,220.87 km) |
| Grande-Synthe to Sitges | 676.15 mi (1,088.16 km) |
| Grande-Synthe to Socuellamos | 846.52 mi (1,362.34 km) |
| Grande-Synthe to Soller | 777.34 mi (1,251.01 km) |
| Grande-Synthe to Solsona | 624.29 mi (1,004.70 km) |
| Grande-Synthe to Son Servera | 788.84 mi (1,269.51 km) |
| Grande-Synthe to Sonseca | 837.84 mi (1,348.37 km) |
| Grande-Synthe to Sopelana | 582.38 mi (937.24 km) |
| Grande-Synthe to Soria | 677.78 mi (1,090.78 km) |
| Grande-Synthe to Suances | 602.13 mi (969.04 km) |
| Grande-Synthe to Sueca | 825.84 mi (1,329.05 km) |
