| Great Wyrley to Sestu | 1,063.17 mi (1,711.00 km) |
| Great Wyrley to Settimo Torinese | 682.60 mi (1,098.55 km) |
| Great Wyrley to Seveso | 697.66 mi (1,122.77 km) |
| Great Wyrley to Sezze | 1,043.57 mi (1,679.46 km) |
| Great Wyrley to Siano | 1,133.49 mi (1,824.18 km) |
| Great Wyrley to Siena | 890.09 mi (1,432.45 km) |
| Great Wyrley to Signa | 857.89 mi (1,380.64 km) |
| Great Wyrley to Silea | 805.17 mi (1,295.80 km) |
| Great Wyrley to Silvi Paese | 1,021.53 mi (1,644.00 km) |
| Great Wyrley to Sinalunga | 908.29 mi (1,461.75 km) |
| Great Wyrley to Siniscola | 1,000.15 mi (1,609.59 km) |
| Great Wyrley to Sinnai | 1,065.60 mi (1,714.91 km) |
| Great Wyrley to Siracusa | 1,362.90 mi (2,193.38 km) |
| Great Wyrley to Solaro | 697.39 mi (1,122.35 km) |
| Great Wyrley to Soliera | 802.45 mi (1,291.42 km) |
